TB-500
Biomatrix Research Labs — TB-500 (10mg)
Overview
Biomatrix Research Labs TB-500 is a high-purity synthetic analogue of the active domain of Thymosin Beta-4 ($\text{T}\beta\text{4}$), a naturally occurring 43-amino acid actin-sequestering protein. Supplied in a 10mg lyophilized format, this peptide fragment is designed for laboratory research into cellular motility, actin filament regulation, dermal and muscular tissue remodeling, and angiogenic pathways.
Product Specifications
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Chemical Name: Acetyl-Leu-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ)
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Molecular Formula: C₃₈H₆₈N₁₀O₁₄
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Total Content: 10mg per vial
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Form: Lyophilized white powder (freeze-dried)
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Purity: ≥99% (HPLC verified)
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Storage: Store at 2°C – 8°C (short-term) or -20°C (long-term). Protect from direct light and moisture.
Primary Research Areas & Mechanisms
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Actin Polymerization & Cell Motility: Investigated for binding to actin monomers (G-actin), preventing premature polymerization and facilitating rapid cell migration directly to sites of microtrauma.
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Tissue Repair & Musculoskeletal Remodeling: Studied in skeletal muscle, cardiac, and dermal assays for its role in cellular differentiation, myofiber survival, and structural extracellular matrix organization.
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Vascular Endothelial Migration: Examined for stimulating endothelial cell proliferation and tube formation, contributing to microvascular repair in damaged tissue beds.
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Inflammatory Cascades & Scar Tissue Modulation: Researched for its capacity to downregulate pro-inflammatory chemokines and modulate excessive myofibroblast differentiation to prevent pathological fibrotic scarring.
Research Disclaimer:
Strictly for laboratory research and in vitro experimentation only. Not for human or veterinary use, medical therapy, or diagnostic applications.