SLU-PP-332

Biomatrix Research Labs — SLU-PP-332 (100mg)

Overview

Biomatrix Research Labs SLU-PP-332 is a high-purity, small-molecule pan-agonist targeting Estrogen-Related Receptors (ERR$\alpha$, ERR$\beta$, and ERR$\gamma$). Known in preclinical literature as a potent metabolic and exercise mimetic tool compound, SLU-PP-332 is synthesized for laboratory investigation into mitochondrial biogenesis, oxidative phosphorylation pathways, fatty acid oxidation, and cellular energy homeostasis.

Product Specifications

• Chemical Name: 4-Hydroxy-$N$'-[(1$E$)-naphthalen-2-ylmethylidene]benzohydrazide

• CAS Number: 303760-60-3

• Molecular Formula: C₁₈H₁₄N₂O₂

• Molecular Weight: 290.32 g/mol

• Total Content: 100mg

• Form: High-purity crystalline powder

• Purity: ≥99% (HPLC & MS verified)

• Solubility: Soluble in DMSO

• Storage: Store at -20°C. Protect from light, moisture, and extreme heat.

Primary Research Areas & Mechanisms

• Pan-ERR Nuclear Receptor Activation: Investigated for its high affinity and agonism across ERR$\alpha$, ERR$\beta$, and ERR$\gamma$ nuclear transcription factors, initiating acute aerobic-like genetic programming in skeletal muscle models.

• Mitochondrial Biogenesis & OXPHOS Upregulation: Studied for enhancing mitochondrial respiration, cytochrome c levels, and electron transport chain complex expression without cellular toxicity.

• Fatty Acid Oxidation & Lipid Metabolism: Examined for upregulating key metabolic genes governing $\beta$-oxidation, shifting substrate utilization toward fatty acid metabolism and reducing lipid accumulation.

• Skeletal Muscle Fiber Transformation: Researched in preclinical assays for promoting the phenotypic shift toward Type IIa oxidative, endurance-adapted muscle fibers.

Research Disclaimer:

Strictly for in vitro, laboratory, and scientific research purposes only. Not intended for human or veterinary use, clinical diagnostics, dietary supplementation, or therapeutic administration.